Applied Technology
AFM vs. STED vs. Light-Sheet: Choosing the Right Microscope for Your Biological Experiment
The choice between Atomic Force Microscopy (AFM), STED, and light-sheet microscopy hinges on whether your experiment requires measuring physical surfaces and mechanics or visualizing fluorescently labeled molecules. Each technique presents unique trade-offs in resolution, sample preparation, and live-cell suitability, guiding the selection based on specific biological questions.
Jina Park·October 14, 2026