Bioinformatics
3 articles
From Bone Powder to Ancient Genome: How Scientists Extract and Authenticate DNA from the Deep Past
Scientists employ a rigorous, multi-stage workflow to extract and authenticate ancient DNA (aDNA) from fossilized remains. This process involves meticulous sample preparation, DNA extraction, and bioinformatic analysis, all guarded by stringent controls to prevent contamination and ensure data reliability.
Unraveling Prehistoric Human Migration: The Methodologies of Ancient DNA Analysis
Ancient DNA (aDNA) analysis provides direct genetic evidence to reconstruct prehistoric human migration and population dynamics. The article details specialized methodologies, from laboratory preparation and sequencing to bioinformatic analysis and population genetic statistics, used to overcome aDNA's challenges and uncover past human mobility and admixture.
What is Computational Systems Biology? Methods and Applications Explained
At MIT, 'Advanced Computational Biology: Genomes, Networks, Evolution' remains an elective, not a core subject, for graduate students.